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Chemical Skin Injury: Mechanisms, Prevention, - download pdf or read online

By Howard I. Maibach, Alan H. Hall

ISBN-10: 3642397786

ISBN-13: 9783642397783

ISBN-10: 3642397794

ISBN-13: 9783642397790

This ebook presents an updated, compact yet finished assessment of chemical dermis accidents, differentiating them from thermal pores and skin burns. After an introductory bankruptcy at the historical past of chemical pores and skin accidents and the scope of the matter, the anatomy, histology, body structure, and immunology of ordinary pores and skin are defined. Mechanisms focused on chemical penetration of ordinary pores and skin are defined, and the results of broken epidermis on chemical penetration are analyzed. the rest of the ebook discusses quite a few clinically appropriate facets, corresponding to different different types of chemical epidermis harm, together with accidents that come up in the course of epidermis peeling or because of hair items; preventive measures; emergency therapy; rinsing treatment; scientific and surgical procedure; and the significance of supplying proper info to employees. The position of predictive toxicology is additionally considered.

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Additional info for Chemical Skin Injury: Mechanisms, Prevention, Decontamination, Treatment

Example text

Silberberg I, Thorbecke GJ, Baer RL, Rosenthal SA, Berezowsky V. Antigen-bearing Langerhans cells in skin, dermal lymphatics and in lymph nodes. Cell Immunol. 1976;25:137–51. 25. Shelley WB, Juhlin L. Langerhans cells from a reticuloepithelial trap for external contact antigens. Nature. 1976;261:46–7. 2 Histology and Immunology of the Skin 26. Bergstresser PR, Fletcher C, Streilein JW. Surface densities of Langerhans cells in relation to rodent epidermal sites with special immunologic properties.

In this manner, one has elaborated the concept of a neuroendocrine-immunocutaneous system which groups the totality of elements present in the skin and their secretions. This concept allows a better understanding of the infinite complexity of a system which is simple in appearance, but which in fact is very complex. Moreover, there exist some specialized nervous structures such as the Meissner bodies as seen in the papillary dermis (specialized in fine touch) and located in the most sensitive areas such as the fingers, the lips, and the tongue and the Pacini bodies which can be observed in the areas submitted to the pressure of the weight of the body.

1980;74:77–80. 27. Schweizer J, Marks F. A developmental study of the distribution and frequency of Langerhans cells in relation to formation of patterning in mouse tail epidermis. J Invest Dermatol. 1977;69:198–204. 28. Toews GB, Bergstresser PR, Streilein JW. Epidermal Langerhans cell density determines whether contact hypersensitivity or un-responsiveness follows skin painting with DNFB. J Immunol. 1980;124:445–53. 29. Streilein JW. Lymphocyte traffic, T cell malignancies and the skin. J Invest Dermatol.

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Chemical Skin Injury: Mechanisms, Prevention, Decontamination, Treatment by Howard I. Maibach, Alan H. Hall


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