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Download e-book for kindle: 20 Things to Know about Deep Brain Stimulation by Erwin B. Montgomery Jr.

By Erwin B. Montgomery Jr.

ISBN-10: 0199338825

ISBN-13: 9780199338825

Twenty issues to grasp approximately Deep mind Stimulation is an intensive and in-depth severe research of the sector of Deep mind Stimulation (DBS) from what many might reflect on a innovative viewpoint. This publication demonstrates the original nature and brilliant promise of DBS and indicates the way it is exceptional as a healing intervention. Dr. Montgomery presents an epistemic research of the presuppositions, assumptions and fallacies underlying present medical realizing of DBS in addition to the body structure and pathophysiology laid low with DBS. reports of the protection and efficacy for a few stipulations, sufferer choices and concerns within the post-operative administration also are integrated. Given the innovative capability and the complexity of DBS in an ever altering healthcare supply context, the ethics of DBS are mentioned intimately.

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Epilepsy Res. 2012;101(3):210–216. 2. 21 Valenstein ES. The War of the Soups and Sparks: The Discovery of Neurotransmitters and the Dispute over How Nerves Communicate. New York: Columbia University Press; 2005. Valldeoriola F, Morsi O, Tolosa E, et al. Prospective comparative study on cost-effectiveness of subthalamic stimulation and best medical treatment in advanced Parkinson’s disease. Mov Disord. 2007;22(15):2183–2191. 3 Deep Brain Stimulation Is Effective for Patients with Parkinson’s Disease J U D G I N G EFFECT I V EN ES S Deep Brain Stimulation (DBS) is remarkably effective for the treatment of Parkinson’s disease.

Dieckmann G. Chronic mediothalamic stimulation for control of phobias. , Ballantine MBA, eds. Modern Concepts in Psychiatric Surgery. Amsterdam: Elsevier; 1979:85–93. Erba G, Moja L, Beghi E, et al. Barriers toward epilepsy surgery: a survey among practicing neurologists. Epilepsia 2012;53(1):35–43. Hilker R, Voges J, Ghaemi M, et al. Deep brain stimulation of the subthalamic nucleus does not increase the striatal dopamine concentration in parkinsonian humans. Mov Disord. 2003;18(1):41–48. Meissner W, Schreiter D, Volkmann J, et al.

In advanced Parkinson’s disease, however, dopamine levels are depleted by more than 99%. Qualitative differences in behavior associated with DBS and behavior associated with levodopa therapy offer indirect evidence that, at least as inferred from the pharmacology, DBS therapeutic effect is not synonymous with neurotransmitter function. Levodopa therapy may cause involuntary movements (dyskinesias). DBS in the vicinity of the globus pallidus interna alleviates them. DBS is not synonymous with surgical ablation, that is, the removal of such “troublemakers” in the brain as putative overactive globus pallidus interna neurons, overactive subthalamic nucleus neurons, or excessive high beta oscillations (oscillations in neuronal activities, typically in local field potentials in the range of 15 Hz to 30 Hz).

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20 Things to Know about Deep Brain Stimulation by Erwin B. Montgomery Jr.

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